Afrah Shafquat, PhD

Join industry and clinical experts as they discuss the transformative potential of computer-based modeling and simulation in clinical trials. This session will explore how virtual human models can predict clinical outcomes, addressing current limitations in clinical development. Discover the applications of ‘In Silico’ clinical trials (ISCT) and the cutting-edge combination of AI methods with computational modeling and simulation to create entire patient cohorts, including synthetic (external) control arms. Through this strategy, the panelists will demonstrate how virtual populations can enhance the trial design and streamline the evaluation of new therapies. Additionally, the panel will discuss collaborative efforts with FDA to develop a playbook for ‘enriching’ clinical trials with frameworks to help accelerate advancements in the field. Attendees of this session will gain a comprehensive understanding of the transformative potential of computer-based modeling and simulation in predicting clinical outcomes. They will leave with insights into the latest advancements shaping the future of clinical trials while mitigating risks and costs, accelerating product approval timelines, and ultimately achieving better patient outcomes.